Phenylpropanoids and polyketides
Cayman Chemical (5Z)-7-Oxozeaenol, Purity: ≥99%, CAS: 253863-19-3, 1 mg
A TAK1 inhibitor (IC50 = 8.1 nM in the presence of TAB1); selective for TAK1 over MEK1 and MEKK1 (IC50s = 411 and 268 nM, respectively), as well as ASK1 and IKKβ at 300 nM; inhibits NF-κB activity in a reporter assay using HEK293 cells expressing TAK1 and TAB1 (IC50 = 83 nM); reduces IL-1-induced increases in COX-2 levels in MEFs; sensitizes HeLa cells to TRAIL-induced apoptosis at 300 nM; induces necroptosis when used in combination with TNF and zVAD in primary mouse BMDMs at 100 nM; topical application prevents picryl chloride-induced increases in ear thickness in mice
Cayman Chemical 5Z 11Z 15R15HydroxyeIcosa
A stable isomer of 15(S)-HETE that elicits contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of PC-3 cells
Apexbio Technology LLC 3,4-Dichloroisocoumarin 51050-59-0 5mg
3 4-Dichloroisocoumarin (CAS 51050-59-0) is a chlorinated derivative of isocoumarin that functions as an inhibitor of serine proteases This compound interacts with the active site serine residue of the enzyme thereby suppressing proteolytic activity Serine proteases play essential roles in various physiological processes including digestion immune response and cell signaling pathways 3 4-Dichloroisocoumarin is widely utilized as a biochemical tool for investigating serine protease function and enzymatic mechanisms in molecular and cellular studies
eMolecules 20958-66-1 | N,N'-DIMETHYL-1,4,5,8-NAPHTHALENETETRACARBOXYLIC DIIMIDE | AstaTech294.266 | C16H10N2O4 | 95.000 | Cn1c(=O)c2ccc(c3c4ccc(c23)c(=O)n(C)c4=O)c1=O | 0.25g | 411901281
N,N'-DIMETHYL-1,4,5,8-NAPHTHALENETETRACARBOXYLIC DIIMIDE | AstaTech | 20958-66-1294.266 | C16H10N2O4 | 95.000 | Cn1c(=O)c2ccc(c3c4ccc(c23)c(=O)n(C)c4=O)c1=O | 0.25g | 411901281
Apexbio Technology LLC 3,4-Dichloroisocoumarin 51050-59-0 10mg
3 4-Dichloroisocoumarin (CAS 51050-59-0) is a chlorinated derivative of isocoumarin that functions as an inhibitor of serine proteases This compound interacts with the active site serine residue of the enzyme thereby suppressing proteolytic activity Serine proteases play essential roles in various physiological processes including digestion immune response and cell signaling pathways 3 4-Dichloroisocoumarin is widely utilized as a biochemical tool for investigating serine protease function and enzymatic mechanisms in molecular and cellular studies
Aobchem (2-Fluoro-5-methylphenyl)(morpholino)methanone | ≥97% | CAS 1249744-58-8 | C12H14FNO2 | 5g
(2-Fluoro-5-methylphenyl)(morpholino)methanone | ≥97% | CAS 1249744-58-8 | C12H14FNO2 | 5g
Aobchem Ethyl 2-(benzyloxy)benzoate | 97% | CAS 63888-93-7 | C16H16O3 | 500mg
Ethyl 2-(benzyloxy)benzoate | 97% | CAS 63888-93-7 | C16H16O3 | 500mg
Aobchem (5-Fluoro-2-methylphenyl)(morpholino)methanone | ≥97% | CAS 864054-89-7 | C12H14FNO2 | 250mg
(5-Fluoro-2-methylphenyl)(morpholino)methanone | ≥97% | CAS 864054-89-7 | C12H14FNO2 | 250mg
Aobchem Methyl 4-(benzylthio)benzoate | ≥97% | CAS 26960-78-1 | C15H14O2S | 5g
Methyl 4-(benzylthio)benzoate | ≥97% | CAS 26960-78-1 | C15H14O2S | 5g
Aobchem (5-Fluoro-2-methylphenyl)(morpholino)methanone | ≥97% | CAS 864054-89-7 | C12H14FNO2 | 5g
(5-Fluoro-2-methylphenyl)(morpholino)methanone | ≥97% | CAS 864054-89-7 | C12H14FNO2 | 5g
Aobchem Ethyl 4-(tert-butyl)benzoate | ≥97% | CAS 5406-57-5 | C13H18O2 | 5g
Ethyl 4-(tert-butyl)benzoate | ≥97% | CAS 5406-57-5 | C13H18O2 | 5g
Apexbio Technology LLC Denatonium benzoate 3734-33-6 100mg
Denatonium benzoate is a small-molecule agonist targeting bitter taste receptors (TAS2Rs) It is designed to activate TAS2Rs thereby initiating intracellular signaling cascades involved in metabolic regulation and immune response Denatonium benzoate exerts its biological activity primarily through binding and activating TAS2Rs expressed on multiple cell populations In laboratory studies Denatonium benzoate demonstrates receptor activation contributing to investigations of taste receptor activation and insulin secretion Based on these pharmacological properties Denatonium benzoate holds research potential in elucidating glucose homeostasis metabolic functions immune cell activation and the role of bitter taste signaling in immunity and allergic responses
Aobchem Methyl 3-(methoxymethyl)benzoate | ≥95% | CAS 1515-87-3 | C10H12O3 | 250mg
Methyl 3-(methoxymethyl)benzoate | ≥95% | CAS 1515-87-3 | C10H12O3 | 250mg
Aobchem Ethyl 4-(2-pyridinyl)benzoate | 95% | CAS 4385-61-9 | C14H13NO2 | 5g
Ethyl 4-(2-pyridinyl)benzoate | 95% | CAS 4385-61-9 | C14H13NO2 | 5g